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Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models
BACKGROUND: Patient-derived tumor models are the new standard for pre-clinical drug testing and biomarker discovery. However, the emerging technology of primary pancreatic cancer organoids has not yet been broadly implemented in research, and complex organotypic models using organoids in co-culture...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870823/ https://www.ncbi.nlm.nih.gov/pubmed/29587663 http://dx.doi.org/10.1186/s12885-018-4238-4 |