Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models

BACKGROUND: Patient-derived tumor models are the new standard for pre-clinical drug testing and biomarker discovery. However, the emerging technology of primary pancreatic cancer organoids has not yet been broadly implemented in research, and complex organotypic models using organoids in co-culture...

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Detalles Bibliográficos
Autores principales: Tsai, Susan, McOlash, Laura, Palen, Katie, Johnson, Bryon, Duris, Christine, Yang, Qiuhui, Dwinell, Michael B., Hunt, Bryan, Evans, Douglas B., Gershan, Jill, James, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870823/
https://www.ncbi.nlm.nih.gov/pubmed/29587663
http://dx.doi.org/10.1186/s12885-018-4238-4

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