Cargando…

The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress

Endoplasmic reticulum (ER) stress is transmitted to mitochondria and is associated with pathologic mitochondrial dysfunction in diverse diseases. The PERK arm of the unfolded protein response (UPR) protects mitochondria during ER stress through the transcriptional and translational remodeling of mit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lebeau, Justine, Saunders, Jaclyn M., Moraes, Vivian W.R., Madhavan, Aparajita, Madrazo, Nicole, Anthony, Mary C., Wiseman, R. Luke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870888/ https://www.ncbi.nlm.nih.gov/pubmed/29539413 http://dx.doi.org/10.1016/j.celrep.2018.02.055

Ejemplares similares

PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid
por: Perea, Valerie, et al.
Publicado: (2023)

PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress
por: Romine, Isabelle C., et al.
Publicado: (2019)

Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators
por: Kline, Gabriel M., et al.
Publicado: (2023)

Divergent Proteome Reactivity Influences Arm-Selective Activation of Pharmacological Endoplasmic Reticulum Proteostasis Regulators
por: Kline, Gabriel M., et al.
Publicado: (2023)

Activation of the Protein Kinase R–Like Endoplasmic Reticulum Kinase (PERK) Pathway of the Unfolded Protein Response after Experimental Traumatic Brain Injury and Treatment with a PERK Inhibitor
por: Brady, Rhys D., et al.
Publicado: (2021)

Knockdown of cytokeratin 8 overcomes chemoresistance of chordoma cells by aggravating endoplasmic reticulum stress through PERK/eIF2α arm of unfolded protein response and blocking autophagy
por: Wang, Di, et al.
Publicado: (2019)

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK and IRE1α-mediated unfolded protein response
por: Jwa, Miri, et al.
Publicado: (2012)

Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum
por: McQuiston, Alexander, et al.
Publicado: (2017)

The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
por: Xiong, Guangyan, et al.
Publicado: (2017)

PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy
por: Salaroglio, Iris C., et al.
Publicado: (2017)

Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders
por: Doyle, Karen M, et al.
Publicado: (2011)

Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling
por: Carrara, Marta, et al.
Publicado: (2015)

Mammalian ECD Protein Is a Novel Negative Regulator of the PERK Arm of the Unfolded Protein Response
por: Olou, Appolinaire A., et al.
Publicado: (2017)

Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response
por: Samali, Afshin, et al.
Publicado: (2010)

The Role of Endoplasmic Reticulum Stress and Unfolded Protein Response in Atherosclerosis
por: Ivanova, Ekaterina A., et al.
Publicado: (2016)

Unfolded Protein Response of the Endoplasmic Reticulum in Tumor Progression and Immunogenicity
por: Yoo, Yoon Seon, et al.
Publicado: (2017)

Endoplasmic Reticulum Unfolded Protein Response, Aging and Exercise: An Update
por: Estébanez, Brisamar, et al.
Publicado: (2018)

Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases
por: Ghemrawi, Rose, et al.
Publicado: (2020)

Endoplasmic Reticulum Stress and Unfolded Protein Response Signaling in Plants
por: Manghwar, Hakim, et al.
Publicado: (2022)

Unfolding the Interactions between Endoplasmic Reticulum Stress and Oxidative Stress
por: Ong, Gideon, et al.
Publicado: (2023)

Activation of the IRE1α Arm, but not the PERK Arm, of the Unfolded Protein Response Contributes to Fumonisin B1-Induced Hepatotoxicity
por: Liu, Xiaoyi, et al.
Publicado: (2020)

Unfolding the Endoplasmic Reticulum of a Social Amoeba: Dictyostelium discoideum as a New Model for the Study of Endoplasmic Reticulum Stress
por: Domínguez-Martín, Eunice, et al.
Publicado: (2018)

Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020)

LRRK2 regulates endoplasmic reticulum–mitochondrial tethering through the PERK‐mediated ubiquitination pathway
por: Toyofuku, Toshihiko, et al.
Publicado: (2019)

Manganese activates autophagy to alleviate endoplasmic reticulum stress–induced apoptosis via PERK pathway
por: Liu, Chang, et al.
Publicado: (2019)

Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response
por: Bernales, Sebastián, et al.
Publicado: (2006)

Unfolded protein stress in the endoplasmic reticulum and mitochondria: a role in neurodegeneration
por: Bernales, Sebastián, et al.
Publicado: (2012)

Membrane lipids and the endoplasmic reticulum unfolded protein response: An interesting relationship
por: Hou, Nicole S, et al.
Publicado: (2014)

Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum
por: Lai, Ya-Shiuan, et al.
Publicado: (2018)

Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate
por: Corazzari, Marco, et al.
Publicado: (2017)

Autophagy, Endoplasmic Reticulum Stress and the Unfolded Protein Response in Intracerebral Hemorrhage
por: Niu, Mingming, et al.
Publicado: (2017)

Endoplasmic reticulum stress and unfolded protein response in infection by intracellular parasites
por: Galluzzi, Luca, et al.
Publicado: (2017)

Mitochondrial retrograde signaling to the endoplasmic-reticulum regulates unfolded protein responses
por: Takeda, Keisuke, et al.
Publicado: (2019)

Crosstalk between endoplasmic reticulum and cytosolic unfolded protein response in tomato
por: Löchli, Karin, et al.
Publicado: (2022)

Uncoupling Proteostasis and Development in Vitro with a Small Molecule Inhibitor of the Pancreatic Endoplasmic Reticulum Kinase, PERK
por: Harding, Heather P., et al.
Publicado: (2012)

Correction: Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020)

Porcine parvovirus replication is suppressed by activation of the PERK signaling pathway and endoplasmic reticulum stress-mediated apoptosis
por: Cao, Liyan, et al.
Publicado: (2020)

Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response
por: McKibbin, Craig, et al.
Publicado: (2012)

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response
por: Schuck, Sebastian, et al.
Publicado: (2009)

Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress
por: Nakato, Ryosuke, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_adl5g0e45b5eds7qkptud0qekm