Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain

Restoring adult stem cell function provides an exciting approach for rejuvenating the aging brain. However, molecular mechanisms mediating neurogenic rejuvenation remain elusive. Here we report that the enzyme ten eleven translocation methylcytosine dioxygenase 2 (Tet2), which catalyzes the producti...

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Detalles Bibliográficos
Autores principales: Gontier, Geraldine, Iyer, Manasi, Shea, Jeremy M., Bieri, Gregor, Wheatley, Elizabeth G., Ramalho-Santos, Miguel, Villeda, Saul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870899/
https://www.ncbi.nlm.nih.gov/pubmed/29466726
http://dx.doi.org/10.1016/j.celrep.2018.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870899/
https://www.ncbi.nlm.nih.gov/pubmed/29466726
http://dx.doi.org/10.1016/j.celrep.2018.02.001

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