Cargando…
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21
Trisomy of chromosome 21, the genetic cause of Down syndrome, has the potential to alter expression of genes on chromosome 21, as well as other locations throughout the genome. These transcriptome changes are likely to underlie the Down syndrome clinical phenotypes. We have employed RNA-seq to under...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870938/ https://www.ncbi.nlm.nih.gov/pubmed/29584757 http://dx.doi.org/10.1371/journal.pone.0194581 |