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Transcriptional signature associated with early rheumatoid arthritis and healthy individuals at high risk to develop the disease

BACKGROUND: Little is known regarding the mechanisms underlying the loss of tolerance in the early and preclinical stages of autoimmune diseases. The aim of this work was to identify the transcriptional profile and signaling pathways associated to non-treated early rheumatoid arthritis (RA) and subj...

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Detalles Bibliográficos
Autores principales: Macías-Segura, N., Castañeda-Delgado, J. E., Bastian, Y., Santiago-Algarra, D., Castillo-Ortiz, J. D., Alemán-Navarro, A. L., Jaime-Sánchez, E., Gomez-Moreno, M., Saucedo-Toral, C. A., Lara-Ramírez, Edgar E., Zapata-Zuñiga, M., Enciso-Moreno, L., González-Amaro, R., Ramos-Remus, C., Enciso-Moreno, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870959/
https://www.ncbi.nlm.nih.gov/pubmed/29584756
http://dx.doi.org/10.1371/journal.pone.0194205