Interaction of microtubule depolymerizing agent indanocine with different human αβ tubulin isotypes

Tubulin isotypes are known to regulate the stability and dynamics of microtubules, and are also involved in the development of resistance against microtubule-targeted cancer drugs. Indanocine, a potent microtubule depolymerizing agent, is highly active against multidrug-resistant (MDR) cancer cells...

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Detalles Bibliográficos
Autores principales: Kumbhar, Bajarang Vasant, Panda, Dulal, Kunwar, Ambarish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870988/
https://www.ncbi.nlm.nih.gov/pubmed/29584771
http://dx.doi.org/10.1371/journal.pone.0194934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870988/
https://www.ncbi.nlm.nih.gov/pubmed/29584771
http://dx.doi.org/10.1371/journal.pone.0194934

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