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Epigenetic regulation of cell fate reprogramming in aging and disease: A predictive computational model
Understanding the control of epigenetic regulation is key to explain and modify the aging process. Because histone-modifying enzymes are sensitive to shifts in availability of cofactors (e.g. metabolites), cellular epigenetic states may be tied to changing conditions associated with cofactor variabi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871006/ https://www.ncbi.nlm.nih.gov/pubmed/29543808 http://dx.doi.org/10.1371/journal.pcbi.1006052 |