Differential effects of divalent cations on elk prion protein fibril formation and stability

Misfolding of the normally folded prion protein of mammals (PrP(C)) into infectious fibrils causes a variety of diseases, from scrapie in sheep to chronic wasting disease (CWD) in cervids. The misfolded form of PrP(C), termed PrP(Sc), or in this case PrP(CWD), interacts with PrP(C) to create more Pr...

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Detalles Bibliográficos
Autores principales: Samorodnitsky, Daniel, Nicholson, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871030/
https://www.ncbi.nlm.nih.gov/pubmed/29310497
http://dx.doi.org/10.1080/19336896.2017.1423187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871030/
https://www.ncbi.nlm.nih.gov/pubmed/29310497
http://dx.doi.org/10.1080/19336896.2017.1423187

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