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Differential effects of divalent cations on elk prion protein fibril formation and stability
Misfolding of the normally folded prion protein of mammals (PrP(C)) into infectious fibrils causes a variety of diseases, from scrapie in sheep to chronic wasting disease (CWD) in cervids. The misfolded form of PrP(C), termed PrP(Sc), or in this case PrP(CWD), interacts with PrP(C) to create more Pr...
Autores principales: | Samorodnitsky, Daniel, Nicholson, Eric M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871030/ https://www.ncbi.nlm.nih.gov/pubmed/29310497 http://dx.doi.org/10.1080/19336896.2017.1423187 |
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