Molecular recognition of flunarizine dihydrochloride and β-cyclodextrin inclusion complex by NMR and computational approaches

BACKGROUND: Flunarizine dihydrochloride (FLN) is used in the prophylactic treatment of migraine, vertigo, occlusive peripheral vascular disease and epilepsy. Cyclodextrins (CDs) are chiral, truncated cone shaped macrocycles known for their inner hydrophobic and outer hydrophilic site. They form comp...

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Detalles Bibliográficos
Autores principales: Upadhyay, Santosh Kumar, Ali, Syed Mashhood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871610/
https://www.ncbi.nlm.nih.gov/pubmed/29589200
http://dx.doi.org/10.1186/s13065-018-0395-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871610/
https://www.ncbi.nlm.nih.gov/pubmed/29589200
http://dx.doi.org/10.1186/s13065-018-0395-4

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