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Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial

BACKGROUND: Sickle-cell disease increases the risk of malnutrition. Low arginine and nitric oxide bioavailability are implicated in morbidity related to sickle-cell disease. Simple interventions are required, especially in low-income settings. We aimed to test the hypotheses that: (1) supplementary...

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Detalles Bibliográficos
Autores principales: Cox, Sharon E, Ellins, Elizabeth A, Marealle, Alphonce I, Newton, Charles R, Soka, Deogratias, Sasi, Philip, Luca Di Tanna, Gian, Johnson, William, Makani, Julie, Prentice, Andrew M, Halcox, Julian P, Kirkham, Fenella J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871644/
https://www.ncbi.nlm.nih.gov/pubmed/29548623
http://dx.doi.org/10.1016/S2352-3026(18)30020-6