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Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial
BACKGROUND: Sickle-cell disease increases the risk of malnutrition. Low arginine and nitric oxide bioavailability are implicated in morbidity related to sickle-cell disease. Simple interventions are required, especially in low-income settings. We aimed to test the hypotheses that: (1) supplementary...
Autores principales: | Cox, Sharon E, Ellins, Elizabeth A, Marealle, Alphonce I, Newton, Charles R, Soka, Deogratias, Sasi, Philip, Luca Di Tanna, Gian, Johnson, William, Makani, Julie, Prentice, Andrew M, Halcox, Julian P, Kirkham, Fenella J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871644/ https://www.ncbi.nlm.nih.gov/pubmed/29548623 http://dx.doi.org/10.1016/S2352-3026(18)30020-6 |
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