Gut Microbiota-Regulated Pharmacokinetics of Berberine and Active Metabolites in Beagle Dogs After Oral Administration

Berberine (BBR) is considered a multi-target drug that has significant advantages. In contrast to its significant pharmacological effects in clinic, the plasma level of BBR is very low. Our previous work revealed that dihydroberberine (dhBBR) could be an absorbable form of BBR in the intestine, and...

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Detalles Bibliográficos
Autores principales: Feng, Ru, Zhao, Zhen-Xiong, Ma, Shu-Rong, Guo, Fang, Wang, Yan, Jiang, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871679/
https://www.ncbi.nlm.nih.gov/pubmed/29618977
http://dx.doi.org/10.3389/fphar.2018.00214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871679/
https://www.ncbi.nlm.nih.gov/pubmed/29618977
http://dx.doi.org/10.3389/fphar.2018.00214

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