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Targeting Endoplasmic Reticulum and/or Mitochondrial Ca(2+) Fluxes as Therapeutic Strategy for HCV Infection

Chronic hepatitis C is characterized by metabolic disorders and by a microenvironment in the liver dominated by oxidative stress, inflammation and regeneration processes that can in the long term lead to liver cirrhosis and hepatocellular carcinoma. Several lines of evidence suggest that mitochondri...

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Detalles Bibliográficos
Autores principales: Scrima, Rosella, Piccoli, Claudia, Moradpour, Darius, Capitanio, Nazzareno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871704/
https://www.ncbi.nlm.nih.gov/pubmed/29619366
http://dx.doi.org/10.3389/fchem.2018.00073