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Targeting Endoplasmic Reticulum and/or Mitochondrial Ca(2+) Fluxes as Therapeutic Strategy for HCV Infection
Chronic hepatitis C is characterized by metabolic disorders and by a microenvironment in the liver dominated by oxidative stress, inflammation and regeneration processes that can in the long term lead to liver cirrhosis and hepatocellular carcinoma. Several lines of evidence suggest that mitochondri...
Autores principales: | Scrima, Rosella, Piccoli, Claudia, Moradpour, Darius, Capitanio, Nazzareno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871704/ https://www.ncbi.nlm.nih.gov/pubmed/29619366 http://dx.doi.org/10.3389/fchem.2018.00073 |
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