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Dicer-like Enzymes with Sequence Cleavage Preferences

Dicer proteins are known to produce small RNAs (sRNAs) from long double-stranded RNA (dsRNA) templates. These sRNAs are bound by Argonaute proteins, which select the guide strand, often with a 5′ end sequence bias. However, Dicer proteins have never been shown to have sequence cleavage preferences....

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Detalles Bibliográficos
Autores principales: Hoehener, Cristina, Hug, Iris, Nowacki, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871716/
https://www.ncbi.nlm.nih.gov/pubmed/29551264
http://dx.doi.org/10.1016/j.cell.2018.02.029