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Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance

Conjugative transposition drives the emergence of multidrug resistance in diverse bacterial pathogens, yet the mechanisms are poorly characterized. The Tn1549 conjugative transposon propagates resistance to the antibiotic vancomycin used for severe drug-resistant infections. Here, we present four hi...

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Detalles Bibliográficos
Autores principales: Rubio-Cosials, Anna, Schulz, Eike C., Lambertsen, Lotte, Smyshlyaev, Georgy, Rojas-Cordova, Carlos, Forslund, Kristoffer, Karaca, Ezgi, Bebel, Aleksandra, Bork, Peer, Barabas, Orsolya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871717/
https://www.ncbi.nlm.nih.gov/pubmed/29551265
http://dx.doi.org/10.1016/j.cell.2018.02.032