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Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury

CNS injury often severs axons. Scar tissue that forms locally at the lesion site is thought to block axonal regeneration, resulting in permanent functional deficits. We report that inhibiting the generation of progeny by a subclass of pericytes led to decreased fibrosis and extracellular matrix depo...

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Detalles Bibliográficos
Autores principales: Dias, David Oliveira, Kim, Hoseok, Holl, Daniel, Werne Solnestam, Beata, Lundeberg, Joakim, Carlén, Marie, Göritz, Christian, Frisén, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871719/
https://www.ncbi.nlm.nih.gov/pubmed/29502968
http://dx.doi.org/10.1016/j.cell.2018.02.004