Moderate Modulation of Cardiac PGC-1α Expression Partially Affects Age-Associated Transcriptional Remodeling of the Heart

Aging is associated with a decline in cardiac function due to a decreased myocardial reserve. This adverse cardiac remodeling comprises of a variety of changes, including a reduction in mitochondrial function and a decline in the expression of the peroxisome proliferator-activated receptor γ coactiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Whitehead, Natasha, Gill, Jonathan F., Brink, Marijke, Handschin, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871735/
https://www.ncbi.nlm.nih.gov/pubmed/29618980
http://dx.doi.org/10.3389/fphys.2018.00242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871735/
https://www.ncbi.nlm.nih.gov/pubmed/29618980
http://dx.doi.org/10.3389/fphys.2018.00242

Ejemplares similares