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Moderate Modulation of Cardiac PGC-1α Expression Partially Affects Age-Associated Transcriptional Remodeling of the Heart

Aging is associated with a decline in cardiac function due to a decreased myocardial reserve. This adverse cardiac remodeling comprises of a variety of changes, including a reduction in mitochondrial function and a decline in the expression of the peroxisome proliferator-activated receptor γ coactiv...

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Detalles Bibliográficos
Autores principales:	Whitehead, Natasha, Gill, Jonathan F., Brink, Marijke, Handschin, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871735/ https://www.ncbi.nlm.nih.gov/pubmed/29618980 http://dx.doi.org/10.3389/fphys.2018.00242

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