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Cementoin–SLPI fusion protein binds to human monocytes and epithelial cells and shows higher biological activity than SLPI

Secretory Leukocyte Proteinase Inhibitor (SLPI) is an antiinflammatory peptide that blocks the activity of serine proteases, primarily the neutrophil elastase. In an attempt to direct the activity of SLPI on inflamed sites, a chimera consisting of the transglutaminase II substrate domain of trappin...

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Detalles Bibliográficos
Autores principales: Maffía, Paulo C., Guerrieri, Diego, Villalonga, Ximena, Caro, Fiorella, Gómez, Sonia, Tateosian, Nancy, Bogado, Betiana P., Sánchez, Mercedes L., Ambrosi, Nella, Chuluyan, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871749/
https://www.ncbi.nlm.nih.gov/pubmed/29593284
http://dx.doi.org/10.1038/s41598-018-23680-0