Automated brightfield morphometry of 3D organoid populations by OrganoSeg

Spheroid and organoid cultures are powerful in vitro models for biology, but size and shape diversity within the culture is largely ignored. To streamline morphometric profiling, we developed OrganoSeg, an open-source software that integrates segmentation, filtering, and analysis for archived bright...

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Detalles Bibliográficos
Autores principales: Borten, Michael A., Bajikar, Sameer S., Sasaki, Nobuo, Clevers, Hans, Janes, Kevin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871765/
https://www.ncbi.nlm.nih.gov/pubmed/29593296
http://dx.doi.org/10.1038/s41598-017-18815-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871765/
https://www.ncbi.nlm.nih.gov/pubmed/29593296
http://dx.doi.org/10.1038/s41598-017-18815-8

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