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Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase

Autophagy emerges as an essential immunity defense against intracellular pathogens. Here we report that turnip mosaic virus (TuMV) infection activates autophagy in plants and that Beclin1 (ATG6), a core component of autophagy, inhibits virus replication. Beclin1 interacts with NIb, the RNA-dependent...

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Detalles Bibliográficos
Autores principales: Li, Fangfang, Zhang, Changwei, Li, Yinzi, Wu, Guanwei, Hou, Xilin, Zhou, Xueping, Wang, Aiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871769/
https://www.ncbi.nlm.nih.gov/pubmed/29593293
http://dx.doi.org/10.1038/s41467-018-03658-2