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A new cell-laden 3D Alginate-Matrigel hydrogel resembles human breast cancer cell malignant morphology, spread and invasion capability observed “in vivo”

Purpose of this study was the development of a 3D material to be used as substrate for breast cancer cell culture. We developed composite gels constituted by different concentrations of Alginate (A) and Matrigel (M) to obtain a structurally stable-in-time and biologically active substrate. Human agg...

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Detalles Bibliográficos
Autores principales: Cavo, Marta, Caria, Marco, Pulsoni, Ilaria, Beltrame, Francesco, Fato, Marco, Scaglione, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871779/
https://www.ncbi.nlm.nih.gov/pubmed/29593247
http://dx.doi.org/10.1038/s41598-018-23250-4