Cargando…

Cell culture-adaptive mutations in hepatitis C virus promote viral production by enhancing viral replication and release

AIM: To explore hepatitis C virus (HCV) adaptive mutations or combinations thereof responsible for enhanced viral production and investigate the underlying mechanisms. METHODS: A series of plasmids with adaptive mutations were constructed. After the plasmids were transfected into Huh7.5 cells, we de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Qi, Li, Yue, Liu, Shun-Ai, Xie, Wen, Cheng, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2018
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871825/ https://www.ncbi.nlm.nih.gov/pubmed/29599605 http://dx.doi.org/10.3748/wjg.v24.i12.1299

Ejemplares similares

Association between polymorphisms of the APOBEC3G gene and chronic hepatitis B viral infection and hepatitis B virus-related hepatocellular carcinoma
por: He, Xiu-Ting, et al.
Publicado: (2017)

Anti-viral role of toll like receptor 4 in hepatitis B virus infection: An in vitro study
por: Das, Dipanwita, et al.
Publicado: (2016)

Sex disparity in viral load, inflammation and liver damage in transgenic mice carrying full hepatitis B virus genome with the W4P mutation in the preS1 region
por: Lee, Seoung-Ae, et al.
Publicado: (2018)

Mutational analysis of hepatitis E virus ORF1 "Y-domain": Effects on RNA replication and virion infectivity
por: Parvez, Mohammad Khalid
Publicado: (2017)

Delta-like ligand 4 in hepatocellular carcinoma intrinsically promotes tumour growth and suppresses hepatitis B virus replication
por: Kunanopparat, Areerat, et al.
Publicado: (2018)

miR-29a promotes hepatitis B virus replication and expression by targeting SMARCE1 in hepatoma carcinoma
por: Wu, Hong-Jie, et al.
Publicado: (2017)

Single amino acid mutation of SR-BI decreases infectivity of hepatitis C virus derived from cell culture in a cell culture model
por: Gao, Rong, et al.
Publicado: (2017)

Construction of a replication-competent hepatitis B virus vector carrying secreted luciferase transgene and establishment of new hepatitis B virus replication and expression cell lines
por: Ruan, Jie, et al.
Publicado: (2019)

(-)-Epigallocatechin-3-gallate enhances poly I:C-induced interferon-λ1 production and inhibits hepatitis C virus replication in hepatocytes
por: Wang, Yi-Zhong, et al.
Publicado: (2017)

Polymorphisms and resistance mutations of hepatitis C virus on sequences in the European hepatitis C virus database
por: Kliemann, Dimas Alexandre, et al.
Publicado: (2016)

Love the one you’re with: replicate viral adaptations converge on the same phenotypic change
por: Miller, Craig R., et al.
Publicado: (2016)

Hepatitis C Viral Replication Complex
por: Li, Hui-Chun, et al.
Publicado: (2021)

Psoralen inhibits hepatitis B viral replication by down-regulating the host transcriptional machinery of viral promoters
por: Ma, Xinna, et al.
Publicado: (2022)

Extracellular Vesicle Release Promotes Viral Replication during Persistent HCV Infection
por: Aydin, Yucel, et al.
Publicado: (2021)

Hepatic microenvironment underlies fibrosis in chronic hepatitis B patients
por: Yao, Qun-Yan, et al.
Publicado: (2020)

Hepatitis C Viral Entry Inhibitors Prolong Viral Suppression by Replication Inhibitors in Persistently-Infected Huh7 Cultures
por: Bush, Caroline O., et al.
Publicado: (2013)

Viral genome changes and the impact of viral genome persistence in myocardium of patients with inflammatory cardiomyopathy
por: Mlejnek, Dalibor, et al.
Publicado: (2018)

Effects of hepatitis E virus infection on interferon production via ISG15
por: Wang, Min, et al.
Publicado: (2018)

Variants in Host Viral Replication Cycle Genes Are Associated With Heterosexual HIV-1 Acquisition in Africans
por: Bigham, Abigail W., et al.
Publicado: (2014)

Long non-coding RNA highly up-regulated in liver cancer promotes exosome secretion
por: Cao, Shun-Qi, et al.
Publicado: (2019)

Potential microRNA panel for the diagnosis and prediction of overall survival of hepatocellular carcinoma with hepatitis B virus infection
por: Zhang, Qi, et al.
Publicado: (2020)

Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats: Molecular study
por: Hasanin, Amany Helmy, et al.
Publicado: (2021)

Primary animal experiment to test the feasibility of a novel Y-Z magnetic hepatic portal blocking band
por: Zhang, Miao-Miao, et al.
Publicado: (2023)

BMI-1 activates hepatic stellate cells to promote the epithelial-mesenchymal transition of colorectal cancer cells
por: Jiang, Zhong-Yang, et al.
Publicado: (2023)

RNA interference targeting the platelet-derived growth factor receptor β subunit ameliorates experimental hepatic fibrosis in rats
por: Chen, Si-Wen, et al.
Publicado: (2008)

Mutations of the SL2 dimerization sequence of the hepatitis C genome abrogate viral replication
por: Masante, Cyril, et al.
Publicado: (2015)

Hepatitis C virus NS5A region mutation in chronic hepatitis C genotype 1 patients who are non-responders to two or more treatments and its relationship with response to a new treatment
por: Muñoz de Rueda, Paloma, et al.
Publicado: (2017)

Angiotensin-converting enzyme 2 improves liver fibrosis in mice by regulating autophagy of hepatic stellate cells
por: Wu, Ying, et al.
Publicado: (2023)

Viral Replication
por: FENNER, FRANK, et al.
Publicado: (1987)

NIM811, a nonimmunosuppressive cyclosporine analogue, suppresses collagen production and enhances collagenase activity in hepatic stellate cells
por: Kohjima, Motoyuki, et al.
Publicado: (2007)

Hemodynamic changes in hepatic sinusoids of hepatic steatosis mice
por: Fan, Jing, et al.
Publicado: (2019)

Calcitriol attenuates liver fibrosis through hepatitis C virus nonstructural protein 3-transactivated protein 1-mediated TGF β1/Smad3 and NF-κB signaling pathways
por: Shi, Liu, et al.
Publicado: (2023)

Alloimmunity But Not Viral Immunity Promotes Allograft Loss in a Mouse Model of Polyomavirus-Associated Allograft Injury
por: Kim, Steven C., et al.
Publicado: (2017)

Hypoxia inducible factor 1α promotes interleukin-1 receptor antagonist expression during hepatic ischemia-reperfusion injury
por: Wang, Zhao-Yang, et al.
Publicado: (2022)

Naturally occurring mutations in the reverse transcriptase region of hepatitis B virus polymerase from treatment-naïve Korean patients infected with genotype C2
por: Kim, Ji-Eun, et al.
Publicado: (2017)

Host Factors Promoting Viral RNA Replication
por: Nagy, Peter D., et al.
Publicado: (2008)

O(6)-methylguanine DNA methyltransferase is upregulated in malignant transformation of gastric epithelial cells via its gene promoter DNA hypomethylation
por: Chen, Yue-Xia, et al.
Publicado: (2022)

Conservation and variability of hepatitis B core at different chronic hepatitis stages
por: Yll, Marçal, et al.
Publicado: (2020)

Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication
por: Triantafilou, Martha, et al.
Publicado: (2022)

Proton pump inhibitors increase the severity of hepatic encephalopathy in cirrhotic patients
por: Fasullo, Matthew, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6apsqm96k3jmccvgufm3d94744