Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

Accumulating evidence indicates that the senescence-associated secretory phenotype (SASP) contributes to many aspects of physiology and disease. Thus, controlling the SASP will have tremendous impacts on our health. However, our understanding of SASP regulation is far from complete. Here, we show th...

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Detalles Bibliográficos
Autores principales: Takahashi, Akiko, Loo, Tze Mun, Okada, Ryo, Kamachi, Fumitaka, Watanabe, Yoshihiro, Wakita, Masahiro, Watanabe, Sugiko, Kawamoto, Shimpei, Miyata, Kenichi, Barber, Glen N., Ohtani, Naoko, Hara, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871854/
https://www.ncbi.nlm.nih.gov/pubmed/29593264
http://dx.doi.org/10.1038/s41467-018-03555-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871854/
https://www.ncbi.nlm.nih.gov/pubmed/29593264
http://dx.doi.org/10.1038/s41467-018-03555-8

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