Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway

Aberrant activation of the Wnt/β-catenin and RAS-extracellular signal-regulated kinase (ERK) pathways play important roles in the tumorigenesis of many different types of cancer, most notably colorectal cancer (CRC). Genes for these two pathways, such as adenomatous polyposis coli (APC) and KRAS are...

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Detalles Bibliográficos
Autores principales: Jeong, Woo-Jeong, Ro, Eun Ji, Choi, Kang-Yell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871897/
https://www.ncbi.nlm.nih.gov/pubmed/29872723
http://dx.doi.org/10.1038/s41698-018-0049-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871897/
https://www.ncbi.nlm.nih.gov/pubmed/29872723
http://dx.doi.org/10.1038/s41698-018-0049-y

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