SUMOylation Regulates Transcription by the Progesterone Receptor A Isoform in a Target Gene Selective Manner

Luminal breast cancers express estrogen (ER) and progesterone (PR) receptors, and respond to endocrine therapies. However, some ER+PR+ tumors display intrinsic or acquired resistance, possibly related to PR. Two PR isoforms, PR-A and PR-B, regulate distinct gene subsets that may differentially influ...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdel-Hafiz, Hany A., Dudevoir, Michelle L., Perez, Daniel, Abdel-Hafiz, Mohamed, Horwitz, Kathryn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871951/
https://www.ncbi.nlm.nih.gov/pubmed/29301281
http://dx.doi.org/10.3390/diseases6010005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871951/
https://www.ncbi.nlm.nih.gov/pubmed/29301281
http://dx.doi.org/10.3390/diseases6010005

Ejemplares similares