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SUMOylation Regulates Transcription by the Progesterone Receptor A Isoform in a Target Gene Selective Manner

Luminal breast cancers express estrogen (ER) and progesterone (PR) receptors, and respond to endocrine therapies. However, some ER+PR+ tumors display intrinsic or acquired resistance, possibly related to PR. Two PR isoforms, PR-A and PR-B, regulate distinct gene subsets that may differentially influ...

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Detalles Bibliográficos
Autores principales:	Abdel-Hafiz, Hany A., Dudevoir, Michelle L., Perez, Daniel, Abdel-Hafiz, Mohamed, Horwitz, Kathryn B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871951/ https://www.ncbi.nlm.nih.gov/pubmed/29301281 http://dx.doi.org/10.3390/diseases6010005

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