Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions

DNA polymerases are essential for genome replication, DNA repair and translesion DNA synthesis (TLS). Broadly, these enzymes belong to two groups: replicative and non-replicative DNA polymerases. A considerable body of data suggests that both groups of DNA polymerases are associated with cancer. Man...

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Detalles Bibliográficos
Autores principales: Shanbhag, Vinit, Sachdev, Shrikesh, Flores, Jacqueline A., Modak, Mukund J., Singh, Kamalendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872031/
https://www.ncbi.nlm.nih.gov/pubmed/29301327
http://dx.doi.org/10.3390/biology7010005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872031/
https://www.ncbi.nlm.nih.gov/pubmed/29301327
http://dx.doi.org/10.3390/biology7010005

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