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The Kiss Switch Brings Inactive R3C Ligase Ribozyme Back to Life

R3C ligase ribozyme catalyzes the nucleophilic attack by a 3′-hydroxyl on a 5′-α-phosphorus of triphosphates to form a 3′-5′-phosphodiester bond. In the present study, although the truncation of R3C ribozyme was accompanied by a large reduction in ligation activity (decrease by two orders of magnitu...

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Detalles Bibliográficos
Autores principales: Tanizawa, Kana, Uchida, Sayuri, Kurihara, Eri, Umehara, Takuya, Tamura, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872033/
https://www.ncbi.nlm.nih.gov/pubmed/29315240
http://dx.doi.org/10.3390/biology7010007