Novel PAMAM-PEG-Peptide Conjugates for siRNA Delivery Targeted to the Transferrin and Epidermal Growth Factor Receptors

The transferrin (TfR) and epidermal growth factor receptors (EGFR) are known to be overexpressed on the surface of a wide variety of tumor cells. Therefore, the peptides B6 (TfR specific) and GE11 (targeted to the EGFR) were linked to the PAMAM (polyamidoamine) structure via a polyethylenglycol (PEG...

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Detalles Bibliográficos
Autores principales: Urbiola, Koldo, Blanco-Fernández, Laura, Ogris, Manfred, Rödl, Wolfgang, Wagner, Ernst, Tros de Ilarduya, Conchita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872078/
https://www.ncbi.nlm.nih.gov/pubmed/29315261
http://dx.doi.org/10.3390/jpm8010004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872078/
https://www.ncbi.nlm.nih.gov/pubmed/29315261
http://dx.doi.org/10.3390/jpm8010004

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