Pharmacogenomic Impact of CYP2C19 Variation on Clopidogrel Therapy in Precision Cardiovascular Medicine

Variability in response to antiplatelet therapy can be explained in part by pharmacogenomics, particularly of the CYP450 enzyme encoded by CYP2C19. Loss-of-function and gain-of-function variants help explain these interindividual differences. Individuals may carry multiple variants, with linkage dis...

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Detalles Bibliográficos
Autores principales: Brown, Sherry-Ann, Pereira, Naveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872082/
https://www.ncbi.nlm.nih.gov/pubmed/29385765
http://dx.doi.org/10.3390/jpm8010008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872082/
https://www.ncbi.nlm.nih.gov/pubmed/29385765
http://dx.doi.org/10.3390/jpm8010008

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