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Establishing a System for Testing Replication Inhibition of the Vibrio cholerae Secondary Chromosome in Escherichia coli

Regulators of DNA replication in bacteria are an attractive target for new antibiotics, as not only is replication essential for cell viability, but its underlying mechanisms also differ from those operating in eukaryotes. The genetic information of most bacteria is encoded on a single chromosome, b...

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Detalles Bibliográficos
Autores principales: Schallopp, Nadine, Milbredt, Sarah, Sperlea, Theodor, Kemter, Franziska S., Bruhn, Matthias, Schindler, Daniel, Waldminghaus, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872114/
https://www.ncbi.nlm.nih.gov/pubmed/29295515
http://dx.doi.org/10.3390/antibiotics7010003