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Differences in Sirtuin Regulation in Response to Calorie Restriction in Cryptococcus neoformans

Cryptococcus neoformans successfully replicates in low glucose in infected patients. In the serotype A strain, H99, growth in this condition prolongs lifespan regulated by SIR2, and can be modulated with SIR2-specific drugs. Previous studies show that lifespan modulation of a cryptococcal population...

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Detalles Bibliográficos
Autores principales: Bouklas, Tejas, Masone, Lindsey, Fries, Bettina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872329/
https://www.ncbi.nlm.nih.gov/pubmed/29463010
http://dx.doi.org/10.3390/jof4010026