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Hyperglycemia Alters the Structure and Hemodynamics of the Developing Embryonic Heart

Congenital heart defects (CHDs) represent the most common form of human birth defects; approximately one-third of heart defects involve malformations of the outflow tract (OFT). Maternal diabetes increases the risk of CHD by 3–5 fold. During heart organogenesis, little is known about the effects of...

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Detalles Bibliográficos
Autores principales: Lawson, Taylor B., Scott-Drechsel, Devon E., Chivukula, Venkat Keshav, Rugonyi, Sandra, Thornburg, Kent L., Hinds, Monica T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872361/
https://www.ncbi.nlm.nih.gov/pubmed/29439517
http://dx.doi.org/10.3390/jcdd5010013