Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues

BACKGROUND: Glioma stem cells (GSCs) are a subpopulation of stem-like cells that contribute to glioblastoma (GBM) aggressiveness, recurrence, and resistance to radiation and chemotherapy. Therapeutically targeting the GSC population may improve patient survival, but unique vulnerabilities need to be...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Dan, Alver, Bonnie M., Li, Shuang, Hlady, Ryan A., Thompson, Joyce J., Schroeder, Mark A., Lee, Jeong-Heon, Qiu, Jingxin, Schwartz, Philip H., Sarkaria, Jann N., Robertson, Keith D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872397/
https://www.ncbi.nlm.nih.gov/pubmed/29587824
http://dx.doi.org/10.1186/s13059-018-1420-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872397/
https://www.ncbi.nlm.nih.gov/pubmed/29587824
http://dx.doi.org/10.1186/s13059-018-1420-6

Ejemplares similares