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Detangling PPI networks to uncover functionally meaningful clusters

BACKGROUND: Decomposing a protein-protein interaction network (PPI network) into non-overlapping clusters or communities, sometimes called “network modules,” is an important way to explore functional roles of sets of genes. When the method to accomplish this decomposition is solely based on purely g...

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Detalles Bibliográficos
Autores principales: Hall-Swan, Sarah, Crawford, Jake, Newman, Rebecca, Cowen, Lenore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872520/
https://www.ncbi.nlm.nih.gov/pubmed/29589565
http://dx.doi.org/10.1186/s12918-018-0550-5