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Three-dimensional experiments and individual based simulations show that cell proliferation drives melanoma nest formation in human skin tissue

BACKGROUND: Melanoma can be diagnosed by identifying nests of cells on the skin surface. Understanding the processes that drive nest formation is important as these processes could be potential targets for new cancer drugs. Cell proliferation and cell migration are two potential mechanisms that coul...

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Detalles Bibliográficos
Autores principales: Haridas, Parvathi, Browning, Alexander P., McGovern, Jacqui A., Sean McElwain, D. L., Simpson, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872522/
https://www.ncbi.nlm.nih.gov/pubmed/29587750
http://dx.doi.org/10.1186/s12918-018-0559-9