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Androgen receptor in advanced breast cancer: is it useful to predict the efficacy of anti-estrogen therapy?

BACKGROUND: Androgen receptor (AR) is widely expressed in breast cancer (BC) but its role in estrogen receptor (ER)-positive tumors is still controversial. The AR/ER ratio has been reported to impact prognosis and response to antiestrogen endocrine therapy (ET). METHODS: We assessed whether AR in pr...

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Detalles Bibliográficos
Autores principales: Bronte, Giuseppe, Rocca, Andrea, Ravaioli, Sara, Puccetti, Maurizio, Tumedei, Maria Maddalena, Scarpi, Emanuela, Andreis, Daniele, Maltoni, Roberta, Sarti, Samanta, Cecconetto, Lorenzo, Fedeli, Anna, Pietri, Elisabetta, De Simone, Valeria, Asioli, Silvia, Amadori, Dino, Bravaccini, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872575/
https://www.ncbi.nlm.nih.gov/pubmed/29587674
http://dx.doi.org/10.1186/s12885-018-4239-3