Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury

BACKGROUND: Neuro–immune interaction underlies chronic neuroinflammation and aberrant sensory processing resulting in neuropathic pain. Despite the pathological significance of both neuroinflammation-driven peripheral sensitization and spinal sensitization, the functional relationship between these...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiguchi, Norikazu, Kobayashi, Daichi, Saika, Fumihiro, Matsuzaki, Shinsuke, Kishioka, Shiroh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872578/
https://www.ncbi.nlm.nih.gov/pubmed/29587798
http://dx.doi.org/10.1186/s12974-018-1133-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872578/
https://www.ncbi.nlm.nih.gov/pubmed/29587798
http://dx.doi.org/10.1186/s12974-018-1133-5

Ejemplares similares