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Elevated polygenic burden for autism is associated with differential DNA methylation at birth

BACKGROUND: Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors, interests, or activities. The etiology of ASD involves both inherited and environmental risk factors, with epigenetic processes h...

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Detalles Bibliográficos
Autores principales: Hannon, Eilis, Schendel, Diana, Ladd-Acosta, Christine, Grove, Jakob, Hansen, Christine Søholm, Andrews, Shan V., Hougaard, David Michael, Bresnahan, Michaeline, Mors, Ole, Hollegaard, Mads Vilhelm, Bækvad-Hansen, Marie, Hornig, Mady, Mortensen, Preben Bo, Børglum, Anders D., Werge, Thomas, Pedersen, Marianne Giørtz, Nordentoft, Merete, Buxbaum, Joseph, Daniele Fallin, M., Bybjerg-Grauholm, Jonas, Reichenberg, Abraham, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872584/
https://www.ncbi.nlm.nih.gov/pubmed/29587883
http://dx.doi.org/10.1186/s13073-018-0527-4