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The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway

The purpose of this study was to investigate the protective mechanism of HDAC2 inhibitor CAY10683 on intestinal mucosal barrier in acute liver failure (ALF). In order to establish ALF-induced intestinal epithelial barrier disruption models, D-galactosamine/LPS and LPS were, respectively, used with r...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Chen, Hui, Chen, Qian, Jiao, Fang-Zhou, Zhang, Wen-Bin, Gong, Zuo-Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872593/
https://www.ncbi.nlm.nih.gov/pubmed/29725271
http://dx.doi.org/10.1155/2018/7859601