Intermittent Hypoxia Increases the Severity of Bleomycin-Induced Lung Injury in Mice

BACKGROUND: Severe obstructive sleep apnea (OSA) with chronic intermittent hypoxia (IH) is common in idiopathic pulmonary fibrosis (IPF). Here, we evaluated the impact of IH on bleomycin- (BLM-) induced pulmonary fibrosis in mice. METHODS: C57BL/6J mice received intratracheal BLM or saline and were...

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Detalles Bibliográficos
Autores principales: Gille, Thomas, Didier, Morgane, Rotenberg, Cécile, Delbrel, Eva, Marchant, Dominique, Sutton, Angela, Dard, Nicolas, Haine, Liasmine, Voituron, Nicolas, Bernaudin, Jean-François, Valeyre, Dominique, Nunes, Hilario, Besnard, Valérie, Boncoeur, Emilie, Planès, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872634/
https://www.ncbi.nlm.nih.gov/pubmed/29725493
http://dx.doi.org/10.1155/2018/1240192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872634/
https://www.ncbi.nlm.nih.gov/pubmed/29725493
http://dx.doi.org/10.1155/2018/1240192

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