Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity

Bone marrow mesenchymal stem cells (BMSCs) are adult multipotent stem cells that can differentiate into mesodermal lineage cells, including adipocytes and osteoblasts. However, the epigenetic mechanisms governing the lineage-specific commitment of BMSCs into adipocytes or osteoblasts are under inves...

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Detalles Bibliográficos
Autores principales: Ali, Dalia, Chalisserry, Elna P., Manikandan, Muthurangan, Hamam, Rimi, Alfayez, Musaad, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872662/
https://www.ncbi.nlm.nih.gov/pubmed/29731773
http://dx.doi.org/10.1155/2018/2379546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872662/
https://www.ncbi.nlm.nih.gov/pubmed/29731773
http://dx.doi.org/10.1155/2018/2379546

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