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Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity
Bone marrow mesenchymal stem cells (BMSCs) are adult multipotent stem cells that can differentiate into mesodermal lineage cells, including adipocytes and osteoblasts. However, the epigenetic mechanisms governing the lineage-specific commitment of BMSCs into adipocytes or osteoblasts are under inves...
Autores principales: | Ali, Dalia, Chalisserry, Elna P., Manikandan, Muthurangan, Hamam, Rimi, Alfayez, Musaad, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872662/ https://www.ncbi.nlm.nih.gov/pubmed/29731773 http://dx.doi.org/10.1155/2018/2379546 |
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