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Site-selective bromination of sp(3) C–H bonds
A method for converting sp(3) C–H to C–Br bonds using an N-methyl sulfamate directing group is described. The reaction employs Rh(2)(oct)(4) and a mixture of NaBr and NaOCl and is performed in aqueous solution open to air. For all sulfamates examined, oxidation occurs with high selectivity at the γ-...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873043/ https://www.ncbi.nlm.nih.gov/pubmed/29629078 http://dx.doi.org/10.1039/c7sc04611a |