Astrocytes expressing ALS‐linked mutant FUS induce motor neuron death through release of tumor necrosis factor‐alpha

Mutations in fused in sarcoma (FUS) are linked to amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease affecting both upper and lower motor neurons. While it is established that astrocytes contribute to the death of motor neurons in ALS, the specific contribution of mutant FUS (mut...

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Detalles Bibliográficos
Autores principales: Kia, Azadeh, McAvoy, Kevin, Krishnamurthy, Karthik, Trotti, Davide, Pasinelli, Piera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873384/
https://www.ncbi.nlm.nih.gov/pubmed/29380416
http://dx.doi.org/10.1002/glia.23298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873384/
https://www.ncbi.nlm.nih.gov/pubmed/29380416
http://dx.doi.org/10.1002/glia.23298

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