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Assessing causal relationships using genetic proxies for exposures: an introduction to Mendelian randomization

BACKGROUND AND AIMS: Studying the consequences of addictive behaviours is challenging, with understanding causal relationships from observational data being particularly difficult. For example, people who smoke or drink excessively are often systematically different from those who do not, are less l...

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Detalles Bibliográficos
Autores principales: Katikireddi, Srinivasa Vittal, Green, Michael J., Taylor, Amy E., Davey Smith, George, Munafò, Marcus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873430/
https://www.ncbi.nlm.nih.gov/pubmed/28921935
http://dx.doi.org/10.1111/add.14038